Article

Single-nucleus RNA-seq of normal-appearing brain regions in relapsing-remitting vs. secondary progressive multiple sclerosis

2022-01-12

Abstract excerpt

<h4>Summary</h4> Multiple sclerosis (MS) is an immune-mediated demyelinating disease that alters central nervous system (CNS) functions. Relapsing-remitting MS (RRMS) is the most common form, which can transform into secondary-progressive MS (SPMS) that is associated with progressive neurodegeneration. Single-nucleus RNA sequencing (snRNA-seq) of MS lesions identified disease-related transcriptomic alterations; h...

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Literature Corpus work: b63fe9d2-59b7-58d9-9e3c-0f0491cbdb4f
DOI: 10.1101/2022.01.10.475705

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