Back to search

Article

The Philadelphia Chromosome, from Negative to Positive: a Case Report of Relapsed Acute Lymphoblastic Leukemia Following Allogeneic Stem Cell Transplantation

2023-03-16

Abstract excerpt

Relapsed acute lymphoblastic leukemia (ALL) represents a continuous challenge for the clinician. Despite recent advances in treatment, the risk of relapse remains significant. The clinical, biological, cytogenetic, and molecular characteristics may be different at the time of relapse. Current comprehensive genome sequencing studies suggest that most relapsed patients, especially those with late relapses, acquire n...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
b62118d2-8c17-5c5c-9344-90190da8d77c
DOI
10.20944/preprints202303.0306.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The Philadelphia Chromosome, from Negative to Positive: a Case Report of Relapsed Acute Lymphoblastic Leukemia Following Allogeneic Stem Cell TransplantationDOI 10.20944/preprints202303.0306.v1
Mutations in epigenetic regulators are involved in acute lymphoblastic leukemia relapse following allogeneic hematopoietic stem cell transplantation.Semantic proximity
Treatment and outcome of Philadelphia chromosome-positive acute lymphoblastic leukemia in adults after relapse.Semantic proximity
Protracted dormancy of pre-leukemic stem cellsSemantic proximity
Philadelphia-like acute lymphoblastic leukemia: the journey from molecular background to the role of bone marrow transplant—review articleSemantic proximity
Importance of measurable residual disease in the outcome of adults with acute lymphoblastic leukemia after allogeneic stem cell transplantation: Long follow-up analysis from a single transplant centerSemantic proximity
A shadow in the treatment of acute leukemia: lineage switchSemantic proximity
AML evolution from preleukemia to leukemia and relapse.Semantic proximity
Role of Allogeneic Hematopoietic Stem Cell Transplantation for Philadelphia Chromosome-Positive B-Cell Acute Lymphoblastic Leukemia in the Contemporary EraSemantic proximity
Allogeneic stem cell transplantation for adult Philadelphia chromosome–negative acute lymphocytic leukemia: comparable survival rates but different risk factors between related and unrelated transplantation in first complete remissionSemantic proximity
Repeated Lineage Switches in an Elderly Case of Refractory B-Cell Acute Lymphoblastic Leukemia With MLL Gene Amplification: A Case Report and Literature ReviewSemantic proximity
Tracing relapse clone reveals complex recurrence patterns of pediatric acute lymphoblastic leukemiaSemantic proximity
[Clinical and biological prognostic factors in relapsed acute myeloid leukemia patients].Semantic proximity
Select a neighboring publication to make it the new centre.