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Article

Maternally transmitted diabetes mellitus associated with the mitochondrial tRNA(Leu(UUR)) A3243G mutation in a four-generation Han Chinese family.

Biochemical and biophysical research communications - 15 Sept 2006

Lu Jianxin, Wang Dawang, Li Ronghua, Li Weixing, Ji Jingzhang, Zhao Jing, Ye Wei, Yang Li, Qian Yaping, Zhu Yi, Guan Min-Xin

Abstract excerpt

We report here the characterization of a four-generation Han Chinese family with maternally transmitted diabetes mellitus. Six (two males/four females) of eight matrilineal relatives in this family exhibited diabetes. The age of onset in diabetes varies from 15 years to 33 years, with an average of 26 years. Two of affected matrilineal relatives also exhibited hearing impairment. Molecular analysis of...

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PMID: 16876129
DOI: 10.1016/j.bbrc.2006.07.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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