Article

Insights into B Cell and Antibody Kinetics Against SARS-CoV-2 Variants Using Mathematical Modelling

2023-11-12

Abstract excerpt

B cells and antibodies are crucial in protecting against infections like SARS-CoV-2. However, antibody levels decline after infection or vaccination, reducing defences against future SARS-CoV-2 infections. To understand antibody production and decline, we developed a mathematical model that predicts germinal center B cell, long-lived plasma cell, memory B cell, and antibody dynamics. Our focus was on B cell activa...

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Literature Corpus work: b60cb7d9-0e86-5ce6-8bc4-db483d630a80
DOI: 10.1101/2023.11.10.566587

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