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Quantifying antibody kinetics and RNA detection during early-phase SARS-CoV-2 infection by time since symptom onset

7 Sept 2020

Abstract excerpt

Understanding and mitigating SARS-CoV-2 transmission hinges on antibody and viral RNA data that inform exposure and shedding, but extensive variation in assays, study group demographics and laboratory protocols across published studies confounds inference of true biological patterns. Our meta-analysis leverages 3214 datapoints from 516 individuals in 21 studies to reveal that seroconversion of both IgG and IgM...

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PMID: 32894217
DOI: 10.7554/elife.60122

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