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Benchmarking circRNA Detection Tools from Long-Read Sequencing Using Data-Driven and Flexible Simulation Framework

2025-04-23

Abstract excerpt

<h4> A bstract </h4> Circular RNAs (circRNAs) are unique non-coding RNAs with covalently closed loop structures formed through backsplicing events. Their stability, tissue-specific expression patterns, and potential as disease biomarkers have garnered increasing attention. However, their circular structure and diverse size range pose challenges for conventional sequencing technologies. Long-read Oxford Nanopore...

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Literature Corpus work: b5fe9f98-bf22-5d9f-8ba3-dca49696382f
DOI: 10.1101/2025.04.17.649290

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