Article

ATF6 enables pathogen infection in ticks by inducing <i>stomatin</i> and altering cholesterol dynamics

2025-01-08

Abstract excerpt

<h4>ABSTRACT</h4> How tick-borne pathogens interact with their hosts has been primarily studied in vertebrates where disease is observed. Comparatively less is known about pathogen interactions within the tick. Here, we report that Ixodes scapularis ticks infected with either Anaplasma phagocytophilum (causative agent of anaplasmosis) or Borrelia burgdorferi (causative agent of Lyme disease) show activation of...

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Literature Corpus work: b5df054c-df74-5840-b155-f0a787f1b565
DOI: 10.1101/2025.01.08.632023

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