Article

Pharmacokinetic Changes and Seizure Outcomes in Pregnant Women Taking Second-Generation Antiepileptic Drugs

2025-12-12

Abstract excerpt

<title>Abstract</title> <p>Purpose The study aims to investigate pharmacokinetic alterations in second-generation antiepileptic drugs (AEDs) and evaluate the relationship between drug blood concentration fluctuations and the seizure control deterioration in pregnant women. Methods A prospective study was conducted in 52 pregnancies with epilepsy. Clinical data of participants including oral daily doses and seizur...

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Literature Corpus work: b5cf45d1-d87b-512d-9c87-a661996849b9
DOI: 10.21203/rs.3.rs-8245797/v1

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