Article

A kinetic ensemble of the Alzheimer’s Aβ peptide

2020-05-08

Abstract excerpt

The discovery that disordered proteins are widespread in the human proteome has prompted the quest for methods to characterize the conformational properties that determine their functional and dysfunctional behaviour. It has become customary to describe these proteins in terms of structural ensembles and free energy landscapes, which offer conformational and thermodynamic insight. However, a current major challeng...

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Literature Corpus work: b5c896cb-30eb-5800-9627-47d20af1dee9
DOI: 10.1101/2020.05.07.082818

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