Article

Chromatin activation as a unifying principle underlying pathogenic mechanisms in multiple myeloma

2019-08-20

Abstract excerpt

<h4>ABSTRACT</h4> Multiple myeloma (MM) is a plasma cell neoplasm associated with a broad variety of genetic lesions. In spite of this genetic heterogeneity, MMs share a characteristic malignant phenotype whose underlying molecular basis remains poorly characterized. In the present study, we examined plasma cells from MM using a multi-epigenomics approach and demonstrated that when compared to normal B cells, mal...

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Literature Corpus work: b5acc73d-ef70-5ecb-a0d0-a2fc2eb0360f
DOI: 10.1101/740027

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