Article

Class III β-Tubulin Overexpression Is a Prominent Mechanism of Paclitaxel Resistance in Ovarian Cancer Patients

2005-01-01

Abstract excerpt

Abstract The vast majority of women with advanced ovarian cancer will ultimately relapse and develop a drug-resistant disease with an overall 5-year survival of &lt;50%. Unfortunately, the mechanisms of drug resistance actually operating in patients are still unknown. To address this issue, in 41 patients affected by advanced ovarian cancer the three main mechanisms of paclitaxel resistance were investigated:...

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Identifiers and source

Literature Corpus work: b589793b-a73e-51ea-8396-981222007019
DOI: 10.1158/1078-0432.298.11.1

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