Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Paclitaxel And Docetaxel Resistance: Molecular Mechanisms and Development of New Generation Taxanes

27 May 2007

Abstract excerpt

Taxanes represent one of the most promising classes of anticancer agents. Unfortunately, their clinical success has been limited by the insurgence of cellular resistance, mainly mediated by the expression of the MDR phenotype or by microtubule alterations. However, the remarkable relevance of paclitaxel and docetaxel in clinical oncology stimulated intensive efforts in the last decade to identify new derivatives...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer therapeutics and mechanisms
Share to Cancer Treatment and Pharmacology
Share to Microtubule and mitosis dynamics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17530726
DOI: 10.1002/cmdc.200600308

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Paclitaxel And Docetaxel Resistance: Molecular Mechanisms and Development of New Generation TaxanesPMID 17530726Read ↗

Key genes and molecular mechanisms related to Paclitaxel ResistanceSemantic proximity Read ↗

Microtubule inhibitors: Differentiating tubulin-inhibiting agents based on mechanisms of action, clinical activity, and resistanceSemantic proximity Read ↗

Taxane resistance in castration-resistant prostate cancer: mechanisms and therapeutic strategiesSemantic proximity Read ↗

Microtubule alterations and resistance to tubulin-binding agents (Review)Semantic proximity Read ↗

Microtubules: A dynamic target in cancer therapySemantic proximity Read ↗

Tubulin: A Target for Antineoplastic Drugs into the Cancer Cells but also in the Peripheral Nervous SystemSemantic proximity Read ↗

Molecular characterisation of isogenic taxane resistant cell lines identify novel drivers of drug resistanceSemantic proximity Read ↗

Resistance to anti-tubulin agents: From vinca alkaloids to epothilonesSemantic proximity Read ↗

Multiple mechanisms underlying acquired resistance to taxanes in selected docetaxel-resistant MCF-7 breast cancer cellsSemantic proximity Read ↗

Molecular mechanisms of docetaxel resistance in prostate cancerSemantic proximity Read ↗

Microtubule Active Agents: Beyond the Taxane FrontierSemantic proximity Read ↗

Mechanisms of Resistance to CabazitaxelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.