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Linking chemical data from the Comparative Toxicogenomics Database with adverse outcome pathways from the AOP-Wiki: a mechanistic data-oriented approach to help inform environmental health

2025-11-17

Abstract excerpt

<h4>Background: </h4> Chemicals can perturb gene functions to affect chronic human diseases, and a significant amount of biological knowledge involved in environmental health is available in public databases. Combining information across resources can assist in the discovery of novel testable hypotheses related to how chemical exposures influence human diseases, such as autism. Methods The Comparative Toxicogenomi...

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Literature Corpus work
b5801200-1b5e-5a66-9d09-b8e8fd5a58c2
DOI
10.12688/f1000research.172567.1
Open publication

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Linking chemical data from the Comparative Toxicogenomics Database with adverse outcome pathways from the AOP-Wiki: a mechanistic data-oriented approach to help inform environmental healthDOI 10.12688/f1000research.172567.1
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