Article

Peptide generative design with weakly order-dependent autoregressive language model and lifelong learning

2024-01-01

Abstract excerpt

Bioactive peptides have become strong candidates for a variety of clinical therapies due to their diverse advantages, which promotes the development of deep generative models for peptide design. Considering that existing methods cannot effectively deal with the conformational flexibility of peptides and are difficult to capture accurate residue-to-residue interaction dependencies, we propose a unified weakly order...

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Literature Corpus work: b5489c8d-12d6-5781-9e85-11e55da47ad1
DOI: 10.1101/2023.12.31.573750

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