Article

Epitope Generation for Peptide-based Cancer Vaccine using Goal-directed Wasserstein Generative Adversarial Network with Gradient Penalty

2023-06-07

Abstract excerpt

<title>Abstract</title> <p>We introduce a novel immunogenicity goal-directed peptide sequence generator in a Wasserstein generative adversarial network (GAN) with gradient penalty. The convolutional neural network-based generator is guided by a critic incorporated with an immunogenicity predictor from DeepImmuno-CNN to generate immunogenic epitopes for bladder cancer vaccines. The convolutional neural network-bas...

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Literature Corpus work: b5330b39-c730-523c-bff9-979a2f757984
DOI: 10.21203/rs.3.rs-3015960/v1

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