Article

Germline mutation rates in young adults predict longevity and reproductive lifespan

2019-08-13

Abstract excerpt

<h4>SUMMARY</h4> <h4>BACKGROUND</h4> Analysis of sequenced genomes from large three-generation families allows de novo mutations identified in Generation II individuals to be attributed to each of their parents’ germlines in Generation I. Because germline mutations increase with age, we hypothesized that they directly limit the duration of childbearing in women, and if correlated with mutation accumulation in soma...

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Literature Corpus work: b51ab15b-f1a5-51c3-898a-43c078249abf
DOI: 10.1101/19004184

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