Human Germline Mutation and the Erratic Evolutionary Clock.

Abstract excerpt

Our understanding of the chronology of human evolution relies on the "molecular clock" provided by the steady accumulation of substitutions on an evolutionary lineage. Recent analyses of human pedigrees have called this understanding into question by revealing unexpectedly low germline mutation rates, which imply that substitutions accrue more slowly than previously believed. Translating mutation rates estimated...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Biological Evolution
• Share to Gene Conversion
• Share to Germ-Line Mutation