Article

Optimizing NK-92 Serial Killers: Gamma Irradiation, CD95/FasLigation, And NK Or LAK Attack Limit Cytotoxic Efficacy

2021-12-28

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> The NK cell line NK-92 and its genetically modified variants are receiving attention as immunotherapies to treat a range of malignancies. However, since NK-92 cells are themselves tumors, they require irradiation prior to transfer and are potentially susceptible to attack by patients’ immune systems. Here, we investigated NK-92 cell-mediated serial killing for t...

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Literature Corpus work: b4bf0568-dc94-5e9d-9f01-37286a817178
DOI: 10.21203/rs.3.rs-1193866/v1

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