Article
Lymphoid irradiation results in long-term increases in natural killer cells in patients treated for Hodgkin's disease.
Cancer - 1 Feb 1992
Macklis R M, Mauch P M, Burakoff S J, Smith B R
Abstract excerpt
Therapeutic lymphoid irradiation has been shown to produce profound long-term alterations in lymphocyte subpopulations and immunologic responsiveness. Dual immunofluorescence flow cytometry and functional cytolytic assays were used to investigate the effects of lymphoid irradiation either alone or in combination with chemotherapy on T-cell and natural killer (NK) cell populations in the blood of patients treated...
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