Article
Lymphoid irradiation results in long-term increases in natural killer cells in patients treated for Hodgkin's disease.
Cancer - 1 Feb 1992
Macklis R M, Mauch P M, Burakoff S J, Smith B R
Abstract excerpt
Therapeutic lymphoid irradiation has been shown to produce profound long-term alterations in lymphocyte subpopulations and immunologic responsiveness. Dual immunofluorescence flow cytometry and functional cytolytic assays were used to investigate the effects of lymphoid irradiation either alone o...
Topics
- Adolescent
- Adult
- Aged
- Antigens, CD
- Antineoplastic Combined Chemotherapy Protocols
- Cell Line
- Child
- Combined Modality Therapy
- Cytotoxicity, Immunologic
- Fluorescent Antibody Technique
- Hodgkin Disease
- Humans
- Killer Cells, Natural
- Middle Aged
- Phenotype
- Splenectomy
- T-Lymphocyte Subsets