Article

Derivation of human primary prostate epithelial cell lines by differentially targeting the CDKN2A locus along with expression of hTERT

2024-05-06

Abstract excerpt

<title>Abstract</title> Prostate cancer (PCa) is the most common cancer diagnosed in men worldwide and the second leading cause of cancer-related deaths in US males in 2022. Prostate cancer also represents the second highest cancer mortality disparity between non-Hispanic blacks and whites. However, there is a relatively small number of prostate normal and cancer cell lines compared to other cancers. To identi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b4b7adf5-9243-53dd-be27-aaf73d1f4912
DOI: 10.21203/rs.3.rs-4294058/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Derivation of human primary prostate epithelial cell lines by differentially targeting the CDKN2A locus along with expression of hTERTDOI 10.21203/rs.3.rs-4294058/v1Read

Immortalization of human primary prostate epithelial cells via CRISPR inactivation of the CDKN2A locus and expression of telomeraseSemantic proximity Read

CELL LINES USED IN PROSTATE CANCER RESEARCH: A COMPENDIUM OF OLD AND NEW LINES—PART 2Semantic proximity Read

CELL LINES USED IN PROSTATE CANCER RESEARCH: A COMPENDIUM OF OLD AND NEW LINES—PART 1Semantic proximity Read

Primary culture and propagation of human prostate epithelial cells.Semantic proximity Read

Patient-derived prostate cancer organoids require α6-integrins for self-renewal and recapitulate genetic heterogeneity and histopathology of the original tumorsSemantic proximity Read

Expanding the Prostate Cancer Cell Line Repertoire with ACRJ-PC28, an AR-negative Neuroendocrine Cell Line Derived From an African-Caribbean PatientSemantic proximity Read

Phenotypic characterization of immortalized normal and primary tumor-derived human prostate epithelial cell cultures.Semantic proximity Read

Molecular characterization of human prostate carcinoma cell linesSemantic proximity Read

In Vivo Models for Prostate Cancer ResearchSemantic proximity Read

Primary cell cultures as models of prostate cancer developmentSemantic proximity Read

hTERT-Immortalized Prostate Epithelial and Stromal-Derived Cells: an Authentic In vitro Model for Differentiation and CarcinogenesisSemantic proximity Read

The neuroendocrine transition in prostate cancer is dynamic and dependent on ASCL1Semantic proximity Read