Article

Differentiation Success of Reprogrammed Cells is Heterogenous <i>In Vivo</i> and Modulated by Somatic Cell Identity Memory

2024-07-09

Abstract excerpt

<h4>Summary</h4> Nuclear reprogramming can change cellular fates. Yet, reprogramming efficiency is low and the resulting cell types are often not functional. Here, we used nuclear transfer to eggs to follow single cells during reprogramming in vivo . We show that the differentiation success of reprogrammed cells varies across cell types and depends on the expression of genes specific to the previous cellular ide...

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Literature Corpus work: b494170d-e783-59a1-9baa-899610f8426c
DOI: 10.1101/2024.07.05.602198

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