Article

Association of Glutamate Receptor Metabotropic 5 Gene (Grm5) Polymorphisms With Schizophrenia Susceptibility and Symptoms in a Chinese-Han Population

2021-03-02

Abstract excerpt

<title>Abstract</title> <p><bold>Objectives: </bold>Metabotropic glutamate receptor subtype 5 (mGluR5) is a potential target for the treatment of schizophrenia (SZ), with the evidence that mGluR5 modulates glutamatergic signaling through the NMDA receptor (NMDAR). Recently it was reported that the <italic>GRM5</italic> gene (encoding mGluR5) is associated with SZ in the Scottish population. <bold>Methods: </bold>...

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Literature Corpus work: b47cbc74-b3a2-5061-afbd-60dd120de071
DOI: 10.21203/rs.3.rs-253495/v1

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