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Identification of ferroptosis-related genes in male mice with sepsis-induced acute lung injury based on transcriptome sequencing

20 Apr 2023

Abstract excerpt

BACKGROUND: Sepsis can result in acute lung injury (ALI). Studies have shown that pharmacological inhibition of ferroptosis can treat ALI. However, the regulatory mechanisms of ferroptosis in sepsis-induced ALI remain unclear. METHODS: Transcriptome sequencing was performed on lung tissue samples from 10 sepsis-induced mouse models of ALI and 10 control mice. After quality control measures, clean data were used...

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PMID: 37081490
DOI: 10.1186/s12890-023-02361-3

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