Article

<i>Enterococcus faecalis</i> CRISPR-Cas is a robust barrier to conjugative antibiotic resistance dissemination in the murine intestine

2018-05-02

Abstract excerpt

CRISPR-Cas systems are barriers to horizontal gene transfer (HGT) in bacteria. Little is known about CRISPR-Cas interactions with conjugative plasmids, and studies investigating CRISPR-Cas/plasmid interactions in in vivo models relevant to infectious disease are lacking. These are significant gaps in knowledge because conjugative plasmids disseminate antibiotic resistance genes among pathogens in vivo , and it i...

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Identifiers and source

Literature Corpus work: b414c426-c799-5470-9526-41215bd8d5df
DOI: 10.1101/312751

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