Back to search

Article

CRISPR-Cas inhibits plasmid transfer and immunizes bacteria against antibiotic resistance acquisition in manure

2023-09-26

Abstract excerpt

The horizontal transfer of antibiotic resistance genes among bacteria is a pressing global issue. The bacterial defense system CRISPR-Cas acts as a barrier to the spread of antibiotic resistance plasmids, and CRISPR-Cas-based antimicrobials can be effective to selectively deplete antibiotic-resistant bacteria. While significant surveillance efforts monitor the spread of antibiotic-resistant bacteria in the clinica...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
4a7ba52f-5cd5-50f7-b390-71a974c59c9f
DOI
10.1101/2023.09.26.559507
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
CRISPR-Cas inhibits plasmid transfer and immunizes bacteria against antibiotic resistance acquisition in manureDOI 10.1101/2023.09.26.559507
<i>Enterococcus faecalis</i> strains with compromised CRISPR-Cas defense emerge under antibiotic selection for a CRISPR-targeted plasmidSemantic proximity
CRISPR-AMRtracker: a novel toolkit to monitor the antimicrobial resistance gene transfer in fecal microbiotaSemantic proximity
Factors affecting CRISPR-Cas defense against antibiotic resistance plasmids harbored by <i>Enterococcus faecalis</i> laboratory model strains and clinical isolatesSemantic proximity
Multidrug-Resistant Enterococci Lack CRISPR- <i>cas</i>Semantic proximity
<i>Enterococcus faecalis</i> CRISPR-Cas is a robust barrier to conjugative antibiotic resistance dissemination in the murine intestineSemantic proximity
An attenuated CRISPR-Cas system in <i>Enterococcus faecalis</i> permits DNA acquisitionSemantic proximity
Effectiveness of CRISPR-Cas in Sensitizing Bacterial Populations with Plasmid-Encoded Antimicrobial ResistanceSemantic proximity
CRISPR-Cas is associated with fewer antibiotic resistance genes in bacterial pathogensSemantic proximity
Mobilome of <i>Enterococcus faecalis</i> from healthy nursery pigs exposed to antibiotic pressureSemantic proximity
CRISPR-Cas and Restriction-Modification Act Additively against Conjugative Antibiotic Resistance Plasmid Transfer in Enterococcus faecalisSemantic proximity
Investigating the prevalence of CRISPR-Cas system and their association with antibiotic resistance genes and virulence factors in Enterococcus faecalis and Enterococcus faecium strains isolated from hospitalized patientsSemantic proximity
CRISPR elements and their association with antimicrobial resistance and virulence genes among vancomycin-resistant and vancomycin-susceptible enterococci recovered from human and food sourcesSemantic proximity
Select a neighboring publication to make it the new centre.