Article

Multi-omics Insights on the Disease Trajectory Linking COPD and Lung Cancer

2026-06-12

Abstract excerpt

<title>Abstract</title> <p>Chronic obstructive pulmonary disease (COPD) and lung cancer (LC) share tobacco exposure and chronic pulmonary inflammation as principal drivers, but the molecular architecture of the trajectory linking the two has not been delineated in a single integrative framework. Drawing on 483,728 UK Biobank participants without baseline COPD or LC, we constructed a four-state, nine-transition mu...

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Literature Corpus work: b4033a05-e7b8-56ad-ab4b-b921d1026bfd
DOI: 10.21203/rs.3.rs-9521865/v1

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