Article
Prediction of local failure by residual tumor cells after radical prostatectomy using retinoic acid receptor beta (RARB) promoter hypermethylation analysis
2025-11-17
Abstract excerpt
<title>Abstract</title> <p> Background Positive surgical margins after radical prostatectomy (RP) are an imperfect surrogate of residual tumor and do not reliably identify men who will experience biochemical recurrence (BCR). Promoter hypermethylation of <italic>retinoic acid receptor beta</italic> gene ( <italic>RARB</italic> ) is a frequent epigenetic alteration in prostate cancer (PCa). We evaluated wheth...
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Identifiers and source
- Literature Corpus work
- b3f28fb6-7410-5216-9657-5bc66dbbd092
- DOI
- 10.21203/rs.3.rs-7877027/v1
