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Article

Methylation of the RARB gene increases prostate cancer risk in black Americans.

The Journal of urology - 1 Jul 2013

Tang Deliang, Kryvenko Oleksandr N, Mitrache Nicoleta, Do Kieu C, Jankowski Michelle, Chitale Dhananjay A, Trudeau Sheri, Rundle Andrew, Belinsky Steven A, Rybicki Benjamin A

Abstract excerpt

PURPOSE: Gene promoter hypermethylation may be useful as a biomarker for cancer risk in histopathologically benign prostate specimens. MATERIALS AND METHODS: We performed a nested case-control study of gene promoter methylation status for 5 genes (APC, RARB, CCND2, RASSF1 and MGMT) measured in benign biopsy specimens from 511 prostate cancer case-control pairs. We estimated the overall and race stratified risk of...

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Source

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Identifiers

PMID: 23376149
DOI: 10.1016/j.juro.2013.01.083
PMCID: PMC3779133

Genes

RARB
APC
CCND2
MGMT
RASSF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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