Article
In utero human cytomegalovirus infection expands NK cell-like FcγRIII-expressing CD8+ T cells that mediate antibody-dependent functions
2023-09-11
Abstract excerpt
Human cytomegalovirus (HCMV) profoundly modulates host T and natural killer (NK) cells across the lifespan, expanding unique effector cells bridging innate and adaptive immunity. Though HCMV is the most common congenital infection worldwide, how this ubiquitous herpesvirus impacts developing fetal T and NK cells remains unclear. Using computational flow cytometry and transcriptome profiling of cord blood from neon...
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Identifiers and source
- Literature Corpus work
- b359fe63-c50b-5bc3-80f6-c4d3c2f1e8e8
- DOI
- 10.1101/2023.09.08.23295279
