Single-cell profiling aligns CD56bright and cytomegalovirus-induced adaptive natural killer cells to a naïve-memory relationship

Abstract excerpt

Development of antigen-specific memory upon pathogen exposure is a hallmark of the adaptive immune system. While natural killer (NK) cells are considered part of the innate immune system, humans exposed to the chronic viral pathogen cytomegalovirus (CMV) often possess a distinct NK cell population lacking in individuals who have not been exposed, termed “adaptive” NK cells. To identify the “naïve” population from...

Topics

Join the communities discussing this publication.

• Cytomegalovirus and herpesvirus research
• Immune Cell Function and Interaction
• T-cell and B-cell Immunology