Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Variability of Human Cytomegalovirus Clinical Isolates Correlates With Altered Expression of Natural Killer Cell-Activating Ligands and IFN-γ.

Frontiers in immunology - 1 Jan 2021

Galitska Ganna, Coscia Alessandra, Forni Diego, Steinbrueck Lars, De Meo Simone, Biolatti Matteo, De Andrea Marco, Cagliani Rachele, Leone Agata, Bertino Enrico, Schulz Thomas, Santoni Angela, Landolfo Santo, Sironi Manuela, Cerboni Cristina, Dell'Oste Valentina

Abstract excerpt

Human cytomegalovirus (HCMV) infection often leads to systemic disease in immunodeficient patients and congenitally infected children. Despite its clinical significance, the exact mechanisms contributing to HCMV pathogenesis and clinical outcomes have yet to be determined. One of such mechanisms involves HCMV-mediated NK cell immune response, which favors viral immune evasion by hindering NK cell-mediated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus
Share to Cytomegalovirus Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytotoxicity, Immunologic

Share to GPI-Linked Proteins

Share to Immune Evasion

Share to Intercellular Signaling Peptides and Proteins

Share to Killer Cells, Natural

Share to NK Cell Lectin-Like Receptor Subfamily K

Source

Open in PubMed Open full text

Identifiers

PMID: 33897679
DOI: 10.3389/fimmu.2021.532484
PMCID: PMC8062705

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Variability of Human Cytomegalovirus Clinical Isolates Correlates With Altered Expression of Natural Killer Cell-Activating Ligands and IFN-γ.PMID 33897679Read ↗

High-Throughput Analysis of Human Cytomegalovirus Genome Diversity Highlights the Widespread Occurrence of Gene-Disrupting Mutations and Pervasive RecombinationSemantic proximity Read ↗

In utero human cytomegalovirus infection expands NK cell-like FcγRIII-expressing CD8+ T cells that mediate antibody-dependent functionsSemantic proximity Read ↗

HCMV-Encoded NK Modulators: Lessons From in vitro and in vivo Genetic VariationSemantic proximity Read ↗

Common Polymorphisms in the Glycoproteins of Human Cytomegalovirus and Associated Strain-Specific ImmunitySemantic proximity Read ↗

Human cytomegalovirus genomics and transcriptomics through the lens of next-generation sequencing: revision and future challengesSemantic proximity Read ↗

Influence of human cytomegalovirus infection on the NK cell receptor repertoire in childrenSemantic proximity Read ↗

Human Cytomegalovirus Genomes Sequenced Directly From Clinical Material: Variation, Multiple-Strain Infection, Recombination, and Gene LossSemantic proximity Read ↗

High-Risk Oncogenic Human CytomegalovirusSemantic proximity Read ↗

Human Cytomegalovirus Genomes Sequenced Directly from Clinical Material: Variation, Multiple-Strain Infection, Recombination and MutationSemantic proximity Read ↗

Influence of congenital human cytomegalovirus infection and the NKG2C genotype on NK‐cell subset distribution in childrenSemantic proximity Read ↗

Human Cytomegalovirus Immune Evasion of Natural Killer Cells: A Virus for All Seasons?Semantic proximity Read ↗

Genomic and Functional Characteristics of Human Cytomegalovirus Revealed by Next-Generation SequencingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.