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Heterochromatin and RNAi act independently to ensure genome stability in Mucorales human fungal pathogens

2022-12-03

Abstract excerpt

Chromatin modifications play a fundamental role in controlling transcription and genome stability and yet despite their importance, are poorly understood in early-diverging fungi. We present the first comprehensive study of histone-lysine and DNA methyltransferases across the Mucoromycota, emphasizing heterochromatin formation pathways that rely on the Clr4 complex involved in H3K9-methylation, the Polycomb-repres...

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Literature Corpus work
b28856f0-bc88-523e-9747-6377994a238b
DOI
10.1101/2022.12.01.518749
Open publication

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Heterochromatin and RNAi act independently to ensure genome stability in Mucorales human fungal pathogensDOI 10.1101/2022.12.01.518749
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