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Early diverging fungus <i>Mucor circinelloides</i> lacks centromeric histone CENP-A and displays a mosaic of point and regional centromeres

2019-07-18

Abstract excerpt

Centromeres are rapidly evolving across eukaryotes, despite performing a conserved function to ensure high fidelity chromosome segregation. CENP-A chromatin is a hallmark of a functional centromere in most organisms. Due to its critical role in kinetochore architecture, the loss of CENP-A is tolerated in only a few organisms, many of which possess holocentric chromosomes. Here, we characterize the consequence of t...

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Literature Corpus work
916d90ff-fc25-5d44-ac33-f0a8134abd19
DOI
10.1101/706580
Open publication

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