Article

Maternal obesity programs white and brown adipose tissue transcriptome and lipidome in offspring in a sex-dependent manner

2021-02-09

Abstract excerpt

<h4>SUMMARY</h4> The prevalence of overweight and obesity among children has drastically increased during the last decades and maternal obesity has been demonstrated as one of the ultimate factors. Nutrition-stimulated transgenerational epigenetic regulation of key metabolic genes is fundamental to the developmental origins of the metabolic syndrome. Fetal nutrition may differently influence female and male offsp...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b27107c2-d605-56cd-abb3-3c39a4ecc5af
DOI: 10.1101/2021.02.08.430188

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Maternal obesity programs white and brown adipose tissue transcriptome and lipidome in offspring in a sex-dependent mannerDOI 10.1101/2021.02.08.430188Read

Maternal high-fat diet programs white and brown adipose tissue lipidome and transcriptome in offspring in a sex- and tissue-dependent manner in miceSemantic proximity Read

Maternal high-fat diet induces long-term obesity with sex-dependent metabolic programming of adipocyte differentiation, hypertrophy and dysfunction in the offspringSemantic proximity Read

Molecular programming modulates hepatic lipid metabolism and adult metabolic risk in the offspring of obese mothers in a sex-specific mannerSemantic proximity Read

Obese mother offspring have hepatic lipidic modulation that contributes to sex-dependent metabolic adaptation later in lifeSemantic proximity Read

Maternal obesity induced metabolic disorders in offspring and myeloid reprogramming by epigenetic regulationSemantic proximity Read

Epigenetic Changes Associated With Obesity-related Metabolic ComorbiditiesSemantic proximity Read

Maternal obesity and fetal metabolic programming: a fertile epigenetic soilSemantic proximity Read

Maternal Western-style diet programs skeletal muscle gene expression in lean adolescent Japanese macaque offspringSemantic proximity Read

Aberrant DNA Methylation Mediates the Transgenerational Risk of Metabolic and Chronic Disease Due to Maternal Obesity and OvernutritionSemantic proximity Read

Childhood obesity from the genes to the epigenome.Semantic proximity Read

Overweight and obesity in pregnancy: their impact on epigeneticsSemantic proximity Read

Sex-Dependent Epigenomic and Transcriptomic Reprogramming Links Maternal Obesity to Cardiac Remodeling in Adult OffspringSemantic proximity Read