Obese mother offspring have hepatic lipidic modulation that contributes to sex-dependent metabolic adaptation later in life

Abstract excerpt

With the increasing prevalence of obesity in women of reproductive age, there is an urgent need to understand the metabolic impact on the fetus. Sex-related susceptibility to liver diseases has been demonstrated but the underlying mechanism remains unclear. Here we report that maternal obesity impacts lipid metabolism differently in female and male offspring. Males, but not females, gained more weight and had...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Adipose Tissue and Metabolism
• Share to Birth, Development, and Health
• Share to Liver Disease Diagnosis and Treatment