Article

Behavioral Efficacy of AAV FOXG1 Gene Replacement Therapy in a Mouse Model of FOXG1 Syndrome

2025-04-03

Abstract excerpt

<h4>ABSTRACT</h4> FOXG1 syndrome is a severe neurodevelopmental disorder characterized by microcephaly, profound intellectual disability with communication deficits including lack of speech, impaired social interaction, increased anxiety, hyperkinetic/dyskinetic movements, seizures and abnormal sleep patterns. Mutations in a single allele of the FOXG1 gene cause disease, likely due to loss-of-function. However,...

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Literature Corpus work: b23971e3-c3c6-5d5e-8cc1-f003533db886
DOI: 10.1101/2025.04.02.646887

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