Article

Leveraging single-cell ATAC-seq to identify disease-critical fetal and adult brain cell types

2021-05-21

Abstract excerpt

Prioritizing disease-critical cell types by integrating genome-wide association studies (GWAS) with functional data is a fundamental goal. Single-cell chromatin accessibility (scATAC-seq) and gene expression (scRNA-seq) have characterized cell types at high resolution, and early work on integrating GWAS with scRNA-seq has shown promise, but work on integrating GWAS with scATAC-seq has been limited. Here, we identi...

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Literature Corpus work: b21bf321-1590-5e36-aa77-c708e85dfca7
DOI: 10.1101/2021.05.20.445067

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