Article
Clinical significance of steroid and xenobiotic receptor and its targeted gene CYP3A4 in human prostate cancer,
2020-06-14
Abstract excerpt
<p>The steroid and xenobiotic receptor (SXR) regulates cytochromeP450 (CYP) enzymes, which are key inactivators of testosterone inthe liver and prostate. In the present study, we investigated SXRexpression in human prostate tissues. We determined SXR immunoreactivityusing an anti-SXR antibody in benign (n = 78) andcancerous (n = 106) tissues obtained by radical prostatectomy.Stained slides were evaluated for the p...
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Identifiers and source
- Literature Corpus work
- b1b756fa-22b1-5afd-8c9b-0865a01e9fa4
- DOI
- 10.31234/osf.io/98rxg
