Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical significance of steroid and xenobiotic receptor and its targeted gene CYP3A4 in human prostate cancer

3 Nov 2011

Abstract excerpt

The steroid and xenobiotic receptor (SXR) regulates cytochrome P450 (CYP) enzymes, which are key inactivators of testosterone in the liver and prostate. In the present study, we investigated SXR expression in human prostate tissues. We determined SXR immunoreactivity using an anti-SXR antibody in benign (n = 78) and cancerous (n = 106) tissues obtained by radical prostatectomy. Stained slides were evaluated for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Transport and Resistance Mechanisms
Share to Hormonal and reproductive studies
Share to Pharmacogenetics and Drug Metabolism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22050110
DOI: 10.1111/j.1349-7006.2011.02143.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical significance of steroid and xenobiotic receptor and its targeted gene CYP3A4 in human prostate cancerPMID 22050110Read ↗

Clinical significance of steroid and xenobiotic receptor and its targeted gene CYP3A4 in human prostate cancer,Semantic proximity Read ↗

SHOX2 promotes prostate cancer proliferation and metastasis through disruption of the Hippo-YAP pathwaySemantic proximity Read ↗

Nuclear receptor TLX functions to promote cancer stemness and EMT in prostate cancer via its direct transactivation of CD44 and stem cell-regulatory transcription factorsSemantic proximity Read ↗

SOXs in human prostate cancer: implication as progression and prognosis factorsSemantic proximity Read ↗

Loss of somatostatin receptor subtype 2 in prostate cancer is linked to an aggressive cancer phenotype, high tumor cell proliferation and predicts early metastatic and biochemical relapse.Semantic proximity Read ↗

Differential expression of peroxiredoxins in prostate cancer: Consistent upregulation of PRDX3 and PRDX4Semantic proximity Read ↗

Expression of the PXR gene in various types of cancer and drug resistanceSemantic proximity Read ↗

Exisulind and related compounds inhibit expression and function of the androgen receptor in human prostate cancer cells.Semantic proximity Read ↗

p63 Cytoplasmic Aberrance is Associated with High Prostate Cancer Stem Cell ExpressionSemantic proximity Read ↗

SOX2 promotes tumorigenesis and increases the anti-apoptotic property of human prostate cancer cellSemantic proximity Read ↗

Steroid and xenobiotic receptor (SXR), cytochrome P450 3A4 and multidrug resistance gene 1 in human adult and fetal tissuesSemantic proximity Read ↗

Gene expression of survivin and its spliced isoforms associated with proliferation and aggressive phenotypes of prostate cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.