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PRKCB is a novel and potential biomarker in colon cancer and shapes an inflamed tumor immune microenvironment

2022-11-28

Abstract excerpt

<h4>Background: </h4> Only a small subset of colon cancer patients with mismatch repair deficiency may also benefit from Immune checkpoint inhibitors (ICIs). New biomarkers correlated with ICIs responsiveness need to be explored. Methods The study data were obtained from TCGA, GEO, cBioPortal, UALCAN, UCSC Xena browser, and CPTAC databases. Protein kinase C beta (PRKCB) was screened via weighted gene co-expressio...

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Literature Corpus work
b16a2638-8c02-5201-89ba-3d91e7b0c80a
DOI
10.21203/rs.3.rs-2296058/v1
Open publication

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PRKCB is a novel and potential biomarker in colon cancer and shapes an inflamed tumor immune microenvironmentDOI 10.21203/rs.3.rs-2296058/v1
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