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Potential Impact of ALKBH5 and YTHDF1 on Tumor Immunity in Colon Adenocarcinoma

17 May 2021

Abstract excerpt

BACKGROUND: ALKBH5 and YTHDF1 are regarded as the eraser and reader, respectively, in N6-methyladenosine (m6A) modification. Recently, immune contexture has been drawing increasing attention in terms of the progression and treatment of cancers. This study aimed to determine the relationship between ALKBH5/YTHDF1 and immunological characteristics of colon adenocarcinoma (COAD). METHODS: Expression of ALKBH5 and...

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PMID: 34079761
DOI: 10.3389/fonc.2021.670490

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