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Apoptotic bodies from patients with Sjögren’s disease drive atypical memory B cell and macrophage activation and autoantibody production

2026-07-20

Abstract excerpt

The impaired clearance of apoptotic cells has long been associated with systemic autoimmune diseases like Sjögren’s disease (SjD), which is characterised by autoantibodies targeting antigens on apoptotic cells. However, most studies analysing human samples have used patient-derived phagocytes and in vitro generated apoptotic cells, which do not reflect the heterogeneity of patient-derived apoptotic bodies (ApoBDs...

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Literature Corpus work
b1672317-0754-5a67-9787-08f3fbb1d577
DOI
10.64898/2026.07.15.738605
Open publication

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Apoptotic bodies from patients with Sjögren’s disease drive atypical memory B cell and macrophage activation and autoantibody productionDOI 10.64898/2026.07.15.738605
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