Article

An amphipathic and cationic antimicrobial peptide kills colistin resistant Gram-negative pathogens <i>in vivo</i>

2021-12-13

Abstract excerpt

New antibiotics are needed against multidrug resistant Gram-negative pathogens that have compromised global health systems. Antimicrobial peptides are generally considered promising lead candidates for the next generation of antibiotics but have not fulfilled this expectation. Here we demonstrate activity of a cationic amphipathic undecapeptide (ChIP; Ch arge change I ndependent P eptide) against a wide panel o...

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Identifiers and source

Literature Corpus work: b14a182e-fa58-5562-aa77-cd059736cd1e
DOI: 10.1101/2021.12.13.472350

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