Article
Combined Analysis of the Prevalence of Drug-Resistant Hepatitis B Virus in Antiviral Therapy-Experienced Patients in Europe (CAPRE).
The Journal of infectious diseases - 1 Jan 2016
Hermans Lucas Etienne, Svicher Valentina, Pas Suzan Diepstraten, Salpini Romina, Alvarez Marta, Ben Ari Ziv, Boland Greet, Bruzzone Bianca, Coppola Nicola, Seguin-Devaux Carole, Dyda Tomasz, Garcia Federico, Kaiser Rolf, Köse Sukran, Krarup Henrik, Lazarevic Ivana, Lunar Maja M, Maylin Sarah, Micheli Valeria, Mor Orna, Paraschiv Simona, Paraskevis Dimitrios, Poljak Mario, Puchhammer-Stöckl Elisabeth, Simon François, Stanojevic Maja, Stene-Johansen Kathrine, Tihic Nijaz, Trimoulet Pascale, Verheyen Jens, Vince Adriana, Weis Nina, Yalcinkaya Tülay, Lepej Snjezana Zidovec, Perno Carlo, Boucher Charles A B, Wensing Annemarie M J
Abstract excerpt
BACKGROUND: European guidelines recommend treatment of chronic hepatitis B virus infection (CHB) with the nucleos(t)ide analogs (NAs) entecavir or tenofovir. However, many European CHB patients have been exposed to other NAs, which are associated with therapy failure and resistance. The CAPRE study was performed to gain insight in prevalence and characteristics of NA resistance in Europe. METHODS: A survey was...
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