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Article

Increased mRNA expression of CDKN2A is a transcriptomic marker of clinically aggressive meningiomas

2022-12-10

Abstract excerpt

<h4>Background</h4> Homozygous loss of CDKN2A/B is a genetic alteration found in many cancer types including meningiomas, where it is associated with poor clinical outcome. It is now also a diagnostic criterion for grade 3 meningiomas in the 2021 WHO classification for central nervous system tumors. However, as in other cancers, the relationship between copy number loss of CDKN2A/B and expression of its gene prod...

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Literature Corpus work
b11c0847-55ff-516e-bd2d-72383020a025
DOI
10.1101/2022.12.07.519545
Open publication

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Increased mRNA expression of CDKN2A is a transcriptomic marker of clinically aggressive meningiomasDOI 10.1101/2022.12.07.519545
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