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TIM3-Mediated Differentiation of IL-10-Producing CD25+ B Cells by Expanded Regulatory T Cells

2025-03-17

Abstract excerpt

<title>Abstract</title> <p> Cell-based immunotherapy utilizing regulatory T cells (Tregs) has recently advanced into clinical applications, demonstrating promising results in phase I/II trials to prevent transplant rejection and treat autoimmune diseases. We have completed a clinical trial in renal transplant patients in which the significant biological effect was the increase of B cells with a regulatory phenot...

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Literature Corpus work: b0e367fb-cd90-5cab-960f-11da05d89033
DOI: 10.21203/rs.3.rs-6135682/v1

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