Article

Reproducing extracellular matrix adverse remodelling of non-ST myocardial infarction in a large animal model

2022-05-19

Abstract excerpt

The rising incidence of non-ST-segment elevation myocardial infarction (NSTEMI) and associated long-term high mortality constitutes an urgent clinical issue. Unfortunately, the study of possible interventions to treat this pathology lacks a reproducible pre-clinical model. Indeed, currently adopted small and large animal models of MI mimic only full-thickness, ST-segment-elevation (STEMI) infarcts, and hence cater...

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Literature Corpus work: b0c8c73b-21b6-541d-a332-d55a78b458ac
DOI: 10.1101/2022.05.19.492645

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