Article
Epigenomic and transcriptomic approaches in the post-genomic era: path to novel targets for diagnosis and therapy of the ischaemic heart? Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart.
Cardiovascular research - 1 Jun 2017
Perrino Cinzia, Barabási Albert-Laszló, Condorelli Gianluigi, Davidson Sean Michael, De Windt Leon, Dimmeler Stefanie, Engel Felix Benedikt, Hausenloy Derek John, Hill Joseph Addison, Van Laake Linda Wilhelmina, Lecour Sandrine, Leor Jonathan, Madonna Rosalinda, Mayr Manuel, Prunier Fabrice, Sluijter Joost Petrus Geradus, Schulz Rainer, Thum Thomas, Ytrehus Kirsti, Ferdinandy Péter
Abstract excerpt
Despite advances in myocardial reperfusion therapies, acute myocardial ischaemia/reperfusion injury and consequent ischaemic heart failure represent the number one cause of morbidity and mortality in industrialized societies. Although different therapeutic interventions have been shown beneficial in preclinical settings, an effective cardioprotective or regenerative therapy has yet to be successfully introduced...
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