Article

Early-life obesogenic environment integrates immunometabolic and epigenetic signatures governing neuroinflammation

2023-04-22

Abstract excerpt

<h4>Early life trauma and obesogenic diet effects of feeding control.</h4> Consumption of a Western-like high-saturated fat diet (WD, 42% kcal from fat) during adolescence in combination with (2) Exposure to early-life psychosocial stress leads to (3) changes in brain neurocircuitry and metabolic dysregulation. These alterations lead to (4) stress susceptibility, (5) emotional and feeding dysregulation, and (6) o...

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Literature Corpus work: b0c7d5e2-e97d-5ded-8244-274aea22988f
DOI: 10.1101/2023.04.21.537874

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