Article
Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence.
Nature - 28 Sept 1995
Adams M D, Kerlavage A R, Fleischmann R D, Fuldner R A, Bult C J, Lee N H, Kirkness E F, Weinstock K G, Gocayne J D, White O
Abstract excerpt
In an effort to identify new genes and analyse their expression patterns, 174,472 partial complementary DNA sequences (expressed sequence tags (ESTs)), totalling more than 52 million nucleotides of human DNA sequence, have been generated from 300 cDNA libraries constructed from 37 distinct organs and tissues. These ESTs have been combined with an additional 118,406 ESTs from the database dbEST, for a total of 83...
Topics
- Adult
- Base Sequence
- Consensus Sequence
- DNA, Complementary
- Databases, Factual
- Female
- Gene Expression
- Gene Library
- Genetic Variation
- Genome, Human
- Humans